During the COVID pandemic, drug overdose deaths rose by almost 30% in the U.S. — the highest number ever recorded, according to the US Centers for Disease Control and Prevention (CDC). We are in the midst of a "fourth wave" of high mortality involving methamphetamine and cocaine use in the United States. This stimulant-related escalation in overdose deaths demands an effective long-term approach. With no FDA-approved medication for Stimulant Use Disorder, the best solution is Contingency Management.